Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance [Array]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185594
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We show that high DCTPP1 expression was associated with cell-intrinsic resistance to nucleoside DNMT inhibition, and that triptolide and its analogs could overcome this resistance. mRNA profiles of DU145 treated with the DNMT inhibitor decitabine alone or in combination with triptolide
创建时间：
2024-10-01
