Ohmyungsamycins (OMSs) A and B are cyclic depsipeptides produced by marine Streptomyces strains, which are synthesized by a non-ribosomal peptide synthetase. Notably, OMS A exhibits more potent activi

NIAID Data Ecosystem60

Metabolomics and transcriptomics guided approaches for system-level understanding and engineering of metabolic network for ascomycin overproduction

代谢工程

抗生素生产优化

Traditionally, it is difficult to identify some non-obvious targets to engineer the Streptomyces hygroscopicus var. ascomyceticus for ascomycin titer improvement. In this project, we developed a novel

NIAID Data Ecosystem30

Streptomyces coelicolor M165 Transcriptome - 1152-29 2-3

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