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Tables S1 to S13 from Identification of Recurrent Activating <i>HER2</i> Mutations in Primary Canine Pulmonary Adenocarcinoma

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Supplementary Table 1. Informatic tools utilized in primary canine lung cancer analysis Supplementary Table 2. Extended clinical and multiplatform annotation of primary canine lung cancer cases. Supplementary Table 3 : Sequencing metrics for primary canine lung cancer exome analysis. Supplementary Table 4. Somatic coding SNVs identified by exome sequencing of primary canine lung cancers. Supplementary Table 5. Somatic copy number variants identified by exome sequencing in primary canine lung cancers. Supplementary Table 6. Somatic coding structural variants identified by exome sequencing of primary canine lung cancers. Supplementary Table 7. Canine genomic regions covered by custom amplicon panel. Supplementary Table 8. Sequencing metrics for primary canine lung cancer amplicon analysis. Supplementary Table 9. Somatic coding SNVs identified by panel sequencing of primary canine lung cancers. Supplementary Table 10. Germline SNPs in COSMIC Tier 1 cancer genes identified by exome and panel sequencing in primary canine lung cancers. Supplementary Table 11. Multi-platform validation of HER2 mutations. Supplementary Table 12. Non-invasive detection of HER2V659E in the plasma of primary canine lung cancer patients. Supplementary Table 13. HER2 protein expression and quantification by immunohistochemistry.

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2019-10-01
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