five

EGAS00001003310 - samples

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NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.omicsdi.org/dataset/ega/EGAD00001004484
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资源简介:
Adeno-associated virus (AAV) is a defective mono-stranded DNA virus, endemic in human population (35-80%). Recurrent clonal AAV2 insertions are associated with the pathogenesis of rare human hepatocellular carcinoma (HCC) developed on normal liver. This study aimed to characterize the natural history of AAV infection in the liver and its consequence in tumor development. In silico analyses using viral capture data explored viral variants and new clonal insertions. Clonal AAV insertions were positive selected during HCC development on non-cirrhotic liver challenging the notion of AAV as a non-pathogenic virus.EGA dataset EGAD00001004484
创建时间:
2023-09-26
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