Crystal structure of JAK3 in complex with Compound 20 (FM484)
收藏Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of JAK3 in complex with Compound 20 (FM484) Descriptor: 1,2-ETHANEDIOL, 1-phenylurea, 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile, ... Authors: Chaikuad, A, Forster, M, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Laufer, S.A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2018-05-23 Release date: 2018-06-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold. J. Med. Chem., 61, 2018
创建时间：
2018-05-23
