DNA polymerase beta substrate complex with incoming 5-FdUTP
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DNA polymerase beta substrate complex with incoming 5-FdUTP Descriptor: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, CHLORIDE ION, ... Authors: Schaich, M.A, Smith, M.R, Cloud, A.S, Holloran, S.M, Freudenthal, B.D. Deposit date: 2017-08-01 Release date: 2017-09-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chem. Res. Toxicol., 30, 2017
本数据集为DNA聚合酶β(DNA polymerase beta)与即将掺入的5-氟脱氧尿苷三磷酸(5-FdUTP)底物复合物。 描述:2'-脱氧-5-氟尿苷5'-(四氢三磷酸酯)、钙离子、氯离子…… 作者:Schaich, M.A、Smith, M.R、Cloud, A.S、Holloran, S.M、Freudenthal, B.D. 提交日期:2017-08-01 发布日期:2017-09-13 最后修改日期:2023-10-04 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.1埃 引用文献:《DNA聚合酶插入治疗性核苷酸类似物的结构》,《化学研究与毒理学》(Chem. Res. Toxicol.),第30卷,2017年



