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Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation [TAIL-Seq]

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP300398
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资源简介:
We revealed that the transcriptome of the mammalian cells under inflammatory status using TAIL-Seq. The reads from wild-type and Tut7-/- BMDMs were mapped to RefSeq mm10 using HISAT2 and trimmed illumina adapter sequences. Finally, using the specific sequences, including Zc3h12a and Il6 to filter out the sequences, and linker-1 to extract the sequences we interested. Overall design: LPS-induced BMDMs mRNA profiles of 7-week-old wild type and Tut7-/- mice were generated by deep sequencing, in duplicate, using Illumina Illumina Hiseq 2000 PE2*150
创建时间:
2021-07-28
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