Catalan et al.Supplemental Material.AJP.25.pdf
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https://figshare.com/articles/dataset/Catalan_et_al_Supplemental_Material_AJP_25_pdf/28498067
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资源简介：
AE4 is a HCO3- transporter that is important for electrolyte transport and pH regulation in epithelia, which has been proposed to mediate Cl-/cation-HCO3- exchange. However, critical residues sustaining transport activity are not known. In this study, we show that AE4 is able to coordinate HCO3- and Na+ or K+ at the TM3-TM10 interface, and that residues T448 and T756 are crucial for cation binding and transport cycle.
创建时间：
2025-02-26
