RNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation. RNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation

Adult cardiac tissue undergoes a rapid process of dedifferentiation when cultured in vitro. The aim of this experiment was to compare the transcriptome of freshly prepared rat myocardial slices with slices cultured in unloaded conditions (no electromechanical stimulation) for 24 hours, electromechanical stimulation @ SL=1.8 for 24 hours & electromechanical stimulation @ SL=2.2 for 24 hours.