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Transcriptional response of thyroid to iodide in wild-type and Nrf2 knockout mice

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE157121
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资源简介:
Analysis of differentially expressed mRNAs indicated that iodide overload upregulated inflammatory-, immune-, fibrosis- and oxidative stress-related pathways, including the Nrf2 pathway. Nrf2 KO mice showed a more pronounced inflammatory-autoimmune transcriptional response to iodide Thyroidal mRNA profiles after iodide exposure (0.05% NaI in their drinking water for 7 days) in C57Bl6j WT and Nrf2 knockout mice
创建时间:
2020-09-07
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