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EphA4 Mediates Pro- and Anti- Tumoral Effects Through Upstream Negative Regulation of AKT in Head and Neck Squamous Cell Carcinoma

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Zenodo2026-06-12 更新2026-06-17 收录
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scRNA data for peripheral blood mononuclear cells (PBMCs) from oral cavity squamous cell carcinoma patients were generated by sequencing with a 10x Genomics fixed scRNA kit (Flex) (RRID:SCR_022938) with raw data processed with 10x Genomics cellranger (RRID:SCR_017344). PBMC samples were obtained from Oliva M, et al., Antitumor immune effects of preoperative sitravatinib and nivolumab in oral cavity cancer: SNOW window-of-opportunity study. J Immunother Cancer. 2021 Oct;9(10):e003476. doi: 10.1136/jitc-2021-003476. PMID: 34599023; PMCID: PMC8488751. Pre represents samples collected before treatment, and Dis represents samples collected after Sitravatinib treatment. Sitravatinib was administered as an oral capsule once daily at a dose of 120 mg. For metadata, please see the paper referenced above.

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2026-06-12
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