Interluminescence: Selective Control of Synaptically-Connected Circuit Elements using bioluminescence

This is the repository for in vivo extracellular electrophysiology testing a bioluminescent-optogenetic synaptic element. In this experiment (see doi: 10.1038/s42003-021-02981-7), extracellular electrophysiology data and 1-photon bioluminescent imaging data were recorded from six PV-Cre mice under isoflurane anesthesia. There are two groups (Opsin(+) and Opsin(-), see session description and doi: 10.1038/s42003-021-02981-7 for details) of 3 animals each. For all animals a baseline of ~3 minutes of data was recorded, after which the bioluminescent luciferin Coelenterazine was infused into a saline well over an open craniotomy exposing barrel cortex. Time Intervals in the data set designate the start and stop times of Coelenterazine infusion in seconds.