RefAHL: A curated quorum sensing reference linking diverse LuxI-type signal synthases with their acyl-homoserine lactone products

Some bacteria use acyl-homoserine lactone (AHL) signals in quorum sensing, a type of cell-cell communication. Here we present “RefAHL”, a curated collection of LuxI-type AHL synthases with their AHL structures and associated metadata. RefAHL is publicly available as a community resource to help catalog LuxI-type diversity encoded in (meta)genomic data.

Methods
The RefAHL dataset was collected, assembled and curated by humans from the public scientific literature.