Novel Solution Phase Strategy for the Synthesis of Chemical Libraries Containing Small Organic Molecules
收藏NIAID Data Ecosystem2026-03-06 收录
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A simple, versatile, and general approach to the solution phase, parallel synthesis of chemical libraries conducted on a generalized or universal template, which allows the preparation of multi-milligram quantities of each individual member, is described. In each step of the sequence, the reactants, unreacted starting material, reagents and their byproducts are removed by simple liquid/liquid or liquid/solid extractions providing the desired intermediates and final compounds in high purities (95% average) irrespective of the reaction yields and without deliberate reaction optimization.
创建时间：
2016-08-18
