One-Step Synthesis of Heteroaromatic-Fused Pyrrolidines via Cyclopropane Ring-Opening Reaction: Application to the PKCβ Inhibitor JTT-010
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https://figshare.com/articles/dataset/One_Step_Synthesis_of_Heteroaromatic_Fused_Pyrrolidines_via_Cyclopropane_Ring_Opening_Reaction_Application_to_the_PKC_Inhibitor_JTT_010/2990962
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资源简介：
A ring-opening reaction of cyclopropanes with five-membered heteroaromatics having a leaving group at C(2) was found to provide heteroaromatic-fused pyrrolidines in one step. This reaction was successfully applied to the synthesis of the protein kinase C-β inhibitor JTT-010, which
possesses a dihydropyrrolo[1,2-a]indole core.
创建时间：
2016-06-03
