Differences in efficacy outcomes in chitosan and placebo groups after intervention.

Median (interquartile range)
§ Mann Whitney test.
Rescue medication defined as any treatment, other than emollient, that was applied in response to a worsening of the disease, corresponding to dosing up treatment; a flare as need of rescue medication for three or more consecutive days; a totally controlled week as a seven-day period without need of rescue treatment and without any days of sleep loss or pruritus score above 4; a well controlled week if rescue treatment and sleep loss or pruritus score above 4 occurred for no more than 2 days, and any other week that did not correspond to the previous definitions of totally and well controlled weeks was classified as no controlled;
Differences in efficacy outcomes in chitosan and placebo groups after intervention.