Amoeboid movement is characteristic for rounded cells, which do not form strong adhesion contacts with the ECM and use blebs as migratory protrusions. It is well known that actin is the main component

NIAID Data Ecosystem60

Gene expression of leaders and laggers MiaPaCa-2 pancreatic cancer cells during perineural invasion

胰腺癌神经侵袭

癌细胞迁移

To investigate the mechanisms of cancer cell migration during perineural invasion in pancreatic cancer, we injected fluorescently labelled MiaPaCA-2 cells in the sciatic nerves and collected the lead

NIAID Data Ecosystem40

Transcriptional analysis in TNFdeltaARE mice to study progression of Crohn's-ileitis and assess relative benefits of global TNF blockade versus TNFR1 targeted modulation

儿科克罗恩病

TNF信号通路

Background and Aims: Crohnâs disease is a debilitating chronic inflammatory disorder of the mammalian gastrointestinal tract. While current therapeutic interventions using anti-TNF biologics show lo

DataONE2022-02-19 更新80

Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration. Homo sapiens

mRNA脱帽功能

癌细胞迁移

The Dcp2 and Nudt16 Nudix hydrolases, are mRNA decapping enzymes that preferentially modulate stability of a subset of mRNAs. Here we report Nudt3 is a third Nudix protein that possess mRNA decapping

NIAID Data Ecosystem60