Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease. Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease

Using RNA-seq we aimed to characterise the transcriptome of patients with PSC-associated IBD relative to patients with ulcerative colitis or healthy. This was performed across multiple tissue locations in order to define tissue-dependent associations.