Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
收藏科学数据银行2023-02-14 更新2026-04-23 收录
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资源简介：
ChemistryPfPI4K kinase purificationBiochemical assayIn vitro inhibition assaysPlasmid constructsCRISPR/Cas9 systemIn vitro inhibition assays of PfPI4K mutated parasitesIn vivo blood-stage inhibition assaysIn vivo plasmodium liver-stage assay
提供机构：
High Magnetic Field Laboratory; Qingsong Liu; Xiaofei Liang; Hefei Institutes of Physical Science
创建时间：
2022-11-03
