DNA damage plays an essential role in the initiation and development of colon cancer. Histone crotonylation is a newly discovered post-translational modification that is thought to promote gene expres

NIAID Data Ecosystem20

Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity

miRNA表达

DNA损伤应答

BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathway

data.nasa.gov2018-06-26 更新50

Data_Sheet_2_Rad9, a 53BP1 Ortholog of Budding Yeast, Is Insensitive to Spo11-Induced Double-Strand Breaks During Meiosis.PDF

DNA损伤应答

酵母遗传学

Exogenous double-strand breaks (DSBs) induce a DNA damage response during mitosis as well as meiosis. The DNA damage response is mediated by a cascade involving Mec1/Tel1 (ATR/ATM) and Rad53 (Chk2) ki

NIAID Data Ecosystem40

Stress response of Saccharomyces cerevisiae to exposure to natural product Azinomycin B.

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