Maternal slimming reprograms metabolic gene expression in mice offspring

ChEBI2012-08-30 更新2026-07-21 收录

母体营养编程

代谢表观遗传学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40479 数据链接链接失效反馈

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Maternal slimming reprograms metabolic gene expression in mice offspring

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2012-08-30

Statistic of RNA-seq DEGs.

代谢表观遗传学

性二态性基因调控

Little is known about how sex and diet interact at the level of chromatin organization. A comprehensive analysis of diet-induced chromatin dynamics can reveal how the liver mounts a rapid adaptive res

NIAID Data Ecosystem30

Data_Sheet_1.PDF

母体营养编程

代谢疾病动物模型

Maternal high-fat or high-salt diets can independently program adverse cardiometabolic outcomes in offspring. However, there is a paucity of evidence examining their effects in combination on metaboli

NIAID Data Ecosystem20

Total RNA from rat hypothalamus sampled at Embryonic day 17 (E17), was sequenced using a 3'DGE (Digital Gene Expression) sequencing approach.. 3'DGE-seq fetal rat hypothalamus

发育转录组学

母体营养编程

We are using a rat model(Rattus norvegicus Sprague Dawley breed) to study the impact of nutritional maternal protein restriction during gestation on the development of the hypothalamus. The hypothalam

NIAID Data Ecosystem10

Intestinal epigenomic alterations are associated with a dysregulated nutrient absorption phenotype in obesity [ATAC-Seq]

代谢表观遗传学

肠道营养吸收表型

Obesity is an epidemic with myriad health effects, but little is understood regarding individual obese phenotypes and how they may respond to therapy. Epigenetic changes associated with obesity have b

NIAID Data Ecosystem20

Maternal sweeteners intake modulates gut microbiota and exacerbates learning and memory processes in adult male offspring

肠道菌群与认知功能

母体营养编程

Background: There is increasing evidence that gut microbiota in offspring is derived in part from maternal environment such as diet. Thus, sweeteners intake including caloric or non-caloric, during pe

Dryad10

Maternal slimming reprograms metabolic gene expression in mice offspring

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