Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid
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Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid Authors: Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. Deposit date: 2013-06-20 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.8 Å) Cite: Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
人类醛糖还原酶（Aldose reductase, AR）与烟酰胺腺嘌呤二核苷酸磷酸（NADP+，NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE）以及{5-氯-2-[(2-氟-4-碘苄基)氨基甲酰]苯氧基}乙酸复合物的晶体结构
描述：醛糖还原酶、烟酰胺腺嘌呤二核苷酸磷酸、{5-氯-2-[(2-氟-4-碘苄基)氨基甲酰]苯氧基}乙酸
作者：Cousido-Siah, A、Mitschler, A、Ruiz, F.X、Fanfrlik, J、Kolar, M、Hobza, P、Podjarny, A
存放日期：2013-06-20
发布日期：2014-04-30
最后修改日期：2023-09-20
实验方法：X射线衍射（0.8埃）
引用文献：《通过卤键调控醛糖还原酶抑制活性》，刊载于Acs Chem.Biol., 8, 2013
创建时间：
2013-06-20
