Total RNA was extracted from WT or KO liver tumor tissues. RNA samples were analyzed by RNA sequencing based on the manufacturer's protocols. Briefly, Illumina HiSeq 2500 platform was used to sequence
Target genes of transcription factor Myc regulated by Mycobacterium tuberculosis EST12 RAW264.7 cells (1×107) were stimulated with 2 μM EST12 for 1 h, then treated or untreated RAW264.7 cells were col
To confirm the relationship between STEAP1 and c-Myc in liver cancer, we analyzed components of c-Myc-related genes after STEAP1 knockdown in HepG2 cells by PCR array. There are two groups: siSTEAP1 a
The functions of key oncogenic transcription factors independent of context have not been fully delineated despite our richer understanding of the genetic alterations in human cancers. The MYC oncogen
Follicular lymphomas and diffuse large B-cell lymphomas have markedly different biological phenotypes and yet all originate from mature, germinal center B-cells. We hypothesized that alterations in DN