Replication of imaging metrics in Parkinson's disease

This data contains imaging data from two cohorts of Parkinson's disease and control subjects, recruited from the Emory Movement Disorders Clinic and scanned on two different MRI scanners. In Cohort 1, imaging data from 19 controls and 22 Parkinson’s disease patients were acquired with a Siemens Trio 3 Tesla scanner using a 2D gradient echo sequence with magnetization transfer preparation pulse. Cohort 2 consisted of 33 controls and 39 Parkinson’s disease patients who were scanned on a Siemens Prisma 3 Tesla scanner with a similar imaging protocol., Cohort 1 data was collected from 2012–2014 and included 19 controls and 22 PD patients. Cohort 2 consisted of 33 healthy controls (HC) and 39 PD patients with data collected from 2015–2016. Controls were recruited from the community and the Emory Alzheimer’s Disease Research Center control population.
MRI data for Cohort 1 were acquired with a Siemens Trio 3 Tesla scanner (Siemens Medical Solutions, Malvern, PA, USA) at Emory University with a 12-channel receive-only head coil. NM-MRI data was acquired using a 2D magnetization transfer (MT) prepared gradient echo (GRE) sequence [13, 14]: echo time (TE) / repetition time (TR) = 2.68 ms / 337 ms, slice thickness 3 mm, in plane resolution 0.39x0.39 mm2, field of view (FOV) = 162–200 mm2, flip angle (FA) = 40°, 470 Hz/pixel bandwidth, 15 contiguous slices, and magnetization transfer preparation pulse (300°, 1.2 kHz off resonance, 10 ms duration), 7 measurements, scan time 16 minutes 17 seconds. For registration from subject space to common ..., Any image processing software (i.e. SPM, FSL, AFNI, ImageJ).