RECOMBINANT DNA CONSTRUCTS AND METHODS FOR MODULATING EXPRESSION OF A TARGET GENE
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
下载链接：
https://www.forestdata.cn/dataDetail.html?id=f7725995-a39c-4af7-83d6-5a048d7bb71e
下载链接
链接失效反馈官方服务：
资源简介：
This invention provides recombinant DNA constructs and methods for manipulating expression of a target gene that is regulated by a small RNA， by interfering with the binding of the small RNA to its target gene. More specifically， this invention discloses recombinant DNA constructs encoding cleavage blockers， 5-modified cleavage blockers， and translational inhibitors useful for modulating expression of a target gene and methods for their use. Further disclosed are miRNA targets useful for designing recombinant DNA constructs including miRNA-unresponsive transgenes， miRNA decoys， cleavage blockers， 5-modified cleavage blockers， and translational inhibitors， as well as methods for their use， and transgenic eukaryotic cells and organisms containing such constructs.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
