CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement)

CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.30 Fab Kappa chain Fv, ... Authors: Ozorowski, G, Turner, H.L, Ward, A.B. Deposit date: 2021-08-16 Release date: 2022-08-24 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022

本数据集为CC6.30 抗原结合片段（fragment antigen binding, Fab）与SARS-CoV-2-6P-Mut7 S蛋白的复合物结构（受体结合域（Receptor Binding Domain, RBD）/可变区片段（variable region fragment, Fv）局部精修）。描述符包括：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、CC6.30 Fab κ链可变区等。作者：Ozorowski G、Turner H.L、Ward A.B。提交日期：2021-08-16；发布日期：2022-08-24；最后修改日期：2025-05-28。实验方法：电子显微镜（分辨率3.8 Å）。引用文献：《工程化SARS-CoV-2中和抗体以提升效力并降低病毒逃逸途径》，《Iscience》，第25卷，2022年。