Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659M Mutation Identified in Cervical Cancer.
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659M Mutation Identified in Cervical Cancer. Descriptor: CITRATE ANION, Fibroblast growth factor receptor 2, MAGNESIUM ION, ... Authors: Chen, H, Mohammadi, M. Deposit date: 2013-02-15 Release date: 2013-08-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2972 Å) Cite: Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep, 4, 2013
宫颈癌中鉴定到的携带致病性功能获得性K659M突变的成纤维细胞生长因子受体2(Fibroblast growth factor receptor 2, FGFR2)激酶域的晶体结构。
表征组分:柠檬酸根阴离子、成纤维细胞生长因子受体2、镁离子……
作者:Chen H、Mohammadi M。
提交日期:2013-02-15;发布日期:2013-08-07;最后修改日期:2023-09-20。
实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.2972埃)。
引用文献:《通过致病性功能获得性突变分析解析内在酪氨酸激酶活性的分子起源》,《细胞报告》(Cell Rep),第4卷,2013年
创建时间:
2013-02-15



