Src kinase in complex with a sulfonamide inhibitor

Src kinase in complex with a sulfonamide inhibitor Descriptor: N-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src Authors: Lebedev, I, Feldman, H.C, Georghiou, G, Maly, D.J, Seeliger, M. Deposit date: 2016-04-03 Release date: 2016-06-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.153 Å) Cite: Structural and Functional Analysis of the Allosteric Modulation of IRE1a with ATP-Competitive Kinase Inhibitors To Be Published

Src激酶（Src kinase）与磺胺类抑制剂的复合物。描述符：N-{4-[8-氨基-3-(异丙基)咪唑并[1,5-a]吡嗪-1-基]萘-1-基}-N'-[3-(三氟甲基)苯基]脲，原癌基因酪氨酸蛋白激酶Src（Proto-oncogene tyrosine-protein kinase Src）。作者：Lebedev I、Feldman H.C、Georghiou G、Maly D.J、Seeliger M。存入日期：2016-04-03，发布日期：2016-06-01，最后修改日期：2023-09-27。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.153埃。引用文献：《ATP竞争性激酶抑制剂对IRE1α变构调控的结构与功能分析》（Structural and Functional Analysis of the Allosteric Modulation of IRE1α with ATP-Competitive Kinase Inhibitors），待发表。