Paired_Nickase

NIAID Data Ecosystem2026-03-12 收录

基因编辑效率

DNA修复

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP318622 数据链接链接失效反馈

官方服务：

资源简介：

Effect of 5' overhang length on paired nickase efficiency; paired nick repair in different DNA repair mutant backgrounds; SSB repair

创建时间：

2021-05-07

Crystal Structure of Human Flap Endonuclease FEN1 (WT) in complex with product 5'-flap DNA, SM3+, and K+

DNA复合物

DNA修复

Crystal Structure of Human Flap Endonuclease FEN1 (WT) in complex with product 5'-flap DNA, SM3+, and K+ Descriptor: DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP

Protein Data Bank Japan2023-09-13 更新70

Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction).

DNA相互作用

DNA修复

Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction).

NIAID Data Ecosystem50

Endonuclease V (nfi) Mutant of Escherichia coli K-12

DNA修复

核酸内切酶V功能研究

Endonuclease V (deoxyinosine 3′ endonuclease), the product of the nfi gene, has a specificity that encompasses DNAs containing dIMP, abasic sites, base mismatches, uracil, and even untreated single-st

PubMed Central50

Additional file 1: of Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes

DNA修复

基因组学

Table S1.Pathway analysis by PANTHER (XLSX 137 kb)

DataCite Commons2020-08-27 更新70

Two hyper base editors: hyABE with increased A-to-G efficiency towards PAM and hyA&C-BEmax with substantially improved A/C simultaneous conversion efficiency.

碱基编辑器优化

基因编辑效率

Base editors, mainly including cytidine base editors(CBE) and adenine base editors(ABE), have been widely used to modify single-base in genomic DNA. The efficiency of A-to-G towards the PAM for ABE an

NIAID Data Ecosystem50

Paired_Nickase

资源简介：

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