Antigen Presentation-Independent Reciprocal Immune Modulation by HLA-DRB1 Allelic Epitopes that Associate with Autoimmune Disease Risk or Protection in Murine Macrophages
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE159820
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资源简介:
We report RNA sequencing data that shows the differential effects of HLA-DRb1*0401 (SE) and HLA-DRb1*0402 (PE) on macrophage gene expression under M1 and M2 polarizing cell culture conditions. mRNA profiles obtained from cells cultured in presence of synthetic peptides coding the 65-79 region of HLA-DRb1*0401 (SE) or HLA-DRb*0402 (PE), and IFNy (for M1) or IL-4 (for M2).
创建时间:
2021-02-02



