Human Sirt6 in complex with ADP-ribose and the inhibitor 2-Pr

Human Sirt6 in complex with ADP-ribose and the inhibitor 2-Pr Descriptor: 2,4-bis(oxidanylidene)-1-[2-oxidanylidene-2-[[(2S)-3-oxidanylidene-3-(propylamino)-2-[3-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)propanoylamino]propyl]amino]ethyl]pyrimidine-5-carboxamide, NAD-dependent protein deacetylase sirtuin-6, SULFATE ION, ... Authors: You, W, Steegborn, C. Deposit date: 2024-07-21 Release date: 2024-08-14 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Elucidating the Unconventional Binding Mode of a DNA-Encoded Library Hit Provides a Blueprint for Sirtuin 6 Inhibitor Development. Chemmedchem, 19, 2024