Crystal structure of CHK1-10pt-mutant complex with compound 9
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Crystal structure of CHK1-10pt-mutant complex with compound 9 Descriptor: 1H-pyrazolo[3,4-d]pyrimidin-4-amine, CHLORIDE ION, Serine/threonine-protein kinase Chk1 Authors: Dokurno, P, Surgenor, A.E, Williamson, D.S. Deposit date: 2021-01-14 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design and Synthesis of Pyrrolo[2,3- d ]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate. J.Med.Chem., 64, 2021
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2021-01-14



