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Synergistic Copper/Enamine Catalysis for the Regio‑, Stereo‑, and Enantioselective Intermolecular α‑Addition of Aldehydes to Allenamides

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NIAID Data Ecosystem2026-03-13 收录
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https://figshare.com/articles/dataset/Synergistic_Copper_Enamine_Catalysis_for_the_Regio_Stereo_and_Enantioselective_Intermolecular_Addition_of_Aldehydes_to_Allenamides/17019024
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资源简介:
We herein describe an intermolecular enantioselective α-addition of aldehydes to allenamides using a dual copper/enamine catalytic system. Highly enantioselective addition of aldehydes was obtained thanks to secondary amine catalysts. The process was found to be highly regio-, stereo-, and enantioselective under mild conditions.
创建时间:
2021-11-15
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