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MRE-SNPs from the filtered set of associations that overlap with validated miRNA-target interactions.

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https://figshare.com/articles/dataset/_MRE_SNPs_from_the_filtered_set_of_associations_that_overlap_with_validated_miRNA_target_interactions_/1583792
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* SNP has been experimentally shown to influence MRE. a SNP effect on miRNA binding: D disrupts an MRE and C creates an MRE. b MAF is based on 1000G pilot 1 CEU population. c Z-scores from a recent eQTL meta-analysis [21] are averaged for LD block (R2 = 1, 1000G pilot 1, CEU); FDR < 0.05 for all associations. d Conservation shows in which species a corresponding MRE is present (polymiRTS v3.0 database). e Supported by AGO-CLIP data. f Validation method: LU- luciferase reporter assay; IM- immunoprecipitation; EX- target expression profiling; CL- CLASH; QP- qRT-PCR; SE- sequencing; PS- pSiLAC; and WE- Western blot. g Association type: C-concordant; U-unconcordant. MRE-SNPs from the filtered set of associations that overlap with validated miRNA-target interactions.
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2015-10-23
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