Early stages of type 1 diabetes (T1D) are characterized by local autoimmune inflammation and progressive loss of insulin-producing pancreatic β cells. We show here that exposure to pro-inflammatory cy
We completed the first genome-wide association study of the age at diagnosis of type 1 diabetes as a quantitative trait. Our analysis found a locus on chromosome 11 containing the SNP rs10833518. Func
Datasets used in the hg38 UCSC session that contains the results from the Nature Genetics article "The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the
1Related SNPs are those in linkage disequilibrium to SNPs within the dataset. 2EX: Exon; DS: Downstream; IN: intron; MS: Missense; NC: Non-coding; NCE: Non-coding exon; NMD: Nonsense-mediated decay; R
