Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion
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https://figshare.com/articles/dataset/Pd-Catalyzed_Spirocyclization_via_C_H_Activation_and_Benzyne_Insertion/4275449
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资源简介:
A palladium-catalyzed
spirocyclization forming spirooxindoles and
spirodihydrobenzofurans has been achieved. Mechanistic studies suggest
that the transformation proceeds through sequential carbopalladation,
C–H activation, and benzyne insertion. Both classes of spirocycles
have been synthesized in good to excellent yields, and the procedure
is readily scalable.
创建时间:
2016-12-01



