Additional file 1 of Serum soluble T cell immunoglobulin mucin domain-3 as an early predictive marker for severity of acute pancreatitis; a retrospective analysis

Additional file 1. A total of 94 acute pancreatitis (AP) patients were enrolled in the current analysis, including 42 (45%), 35 (37%), and 17 (18%) patients were diagnosed as mild acute pancreatitis (MAP), moderately severe acute pancreatitis (MSAP), and severe acute pancreatitis (SAP). General information, including gender, age, Etiology (Biliary, Hypertriglyceridemia, Alcoholic , and Other), body mass index (BMI), pre-existing comorbidities (diabetes mellitus, hypertension, and high triglyceride), and substance abuse (alcohol and tobacco) and Length of hospital stay were collected from the medical chart of AP patients (0 means no, 1 means yes). On admission, vital sign (temperature, heart rate, Breathe, oxygen saturation, Mean arterial pressure) were recorded. Blood samples were obtained from AP patients for blood tests within 24 h of admission. Serological tests included serum concentrations of white blood cells (WBCs), red blood cells (RBCs), Hematocrit, platelet, C-reactive protein (CRP), aspartate and alanine aminotransferases (AST and ALT), Total and Direct bilirubin (TB and DB), urea, creatinine, procalcitonin (PCT), and serum activities of amylase. Various severity scoring systems, including acute physiology and chronic health evaluation II (APACHE II) score, bedside index for severity in acute pancreatitis (BISAP) score, and modified computed tomography severity index (MCTSI) score, were made during the first 24 h. Soluble T cell immunoglobulin and mucin domain-3 (sTIM-3), Serum inflammatory cytokine interleukin-6 (IL-6), interleukin-10 (IL-10) levels were determined using the corresponding commercial ELISA kits..