Secondary responses to IgV-MOG elicited chronic atypical EAE in Lewis rats.
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aLewis rats were immunized with 50 µg GP69-88 (n = 12) or 200 µg rat IgV-MOG (n = 12) in CFA on day 0. On day 28, GP69-88-immunized rats were (n = 5) or were not (n = 6) boosted with 50 µg GP69-88 in IFA, and IgV-MOG-immunized rats were (n = 4) or were not (n = 5) boosted with 200 µg rat IgV-MOG in IFA. Rats were scored daily for clinical signs of EAE. Classical and atypical EAE are defined in the Materials and Methods section.Secondary responses to IgV-MOG elicited chronic atypical EAE in Lewis rats.
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2015-12-02
