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Single-cell transcriptomics reveals early emergence of liver parenchymal and non-parenchymal cell lineages

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To characterize the heterogeneity within endothelial, mesenchymal, and hepatic lineages through formation of the embryonic mouse liver bud, we have performed single-cell RNA sequencing on mouse embryos, spanning days 9.5 to 10.5 of development. This data set includes 12,470 cells with a mean detected gene number of 4,588.

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