Selectivity of Br/Li Exchange and Deprotonation of 4,4′-Dibromo-3,3′-bithiophene for Synthesis of Symmetrical and Unsymmetrical Dithienoheteroaromatic Rings
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Selectivity_of_Br_Li_Exchange_and_Deprotonation_of_4_4_Dibromo_3_3_bithiophene_for_Synthesis_of_Symmetrical_and_Unsymmetrical_Dithienoheteroaromatic_Rings/2433727
下载链接
链接失效反馈官方服务：
资源简介：
The novel selective synthesis of symmetrical and unsymmetrical
dithienoheteroaromatic rings (DTHAs) has been developed
via intramolecular cyclization of 4,4′-dibromo-3,3′-bithiophene
(3). Four reaction conditions including n-BuLi/Et2O, n-BuLi/THF, s-BuLi/Et2O, and t-BuLi/Et2O were employed to react with 3 for selective formation
of two types of dicarbanions, which generate the symmetrical and unsymmetrical DTHAs after quenching with three electrophilic reagents (4a–c). The possible mechanism of formation
of DTHAs was proposed. In addition, two unsymmetrical DTHAs were confirmed by X-ray single-crystal analyses.
创建时间：
2016-02-19
