Results of multivariable MR with ER+ or ER− BC as the outcome.

For each test, 5 traits were used as the exposure traits and ER+ or ER− BC as the outcome. Results are after genetic instrument pruning. Lipid summary statistics are from MVP. N_SNPs: number of genetic instruments used in MR test; CI_95_L: lower bound of 95% CI; CI_95_U: upper bound of 95% CI; P: P-value of MR test. BC, breast cancer; BMI, body mass index; CI, confidence interval; ER, estrogen receptor; HDL, high-density lipoprotein; GLGC, Global Lipids Genetics Consortium; LDL, low-density lipoprotein; MR, Mendelian randomization; MVP, Million Veteran Program; OR, odds ratio; TG, triglycerides.
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