Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (5GW) and H-antigen acceptor
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Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (5GW) and H-antigen acceptor Descriptor: 5-phenyluridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... Authors: Palcic, M.M, Jorgensen, R. Deposit date: 2011-12-08 Release date: 2013-01-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
岩藻糖基半乳糖苷α-N-乙酰半乳糖胺基转移酶(GTA,cisAB突变体L266G、G268A)与新型UDP-Gal衍生抑制剂(5GW)及H抗原受体的共晶结构。描述符:5-苯基尿苷5'-(三氢二磷酸)、组织血型ABO系统转移酶、锰(II)离子…… 作者:Palcic, M.M.、Jorgensen, R. 提交日期:2011年12月8日,发布日期:2013年1月23日,最后修改日期:2023年9月13日。实验方法:X射线衍射(分辨率1.68 Å)。引用文献:《碱基修饰供体类似物揭示糖基转移酶的新型动态特征》,《Journal of Biological Chemistry》(J.Biol.Chem.),288卷,2013年
创建时间:
2011-12-08



