five

Single-nucleus sequencing data from developing and adult mouse olivocochlear neurons

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214027
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Transcriptional diversity of mouse olivocochlear neurons (OCNs) was examined using single-nucleus sequencing of brainstem cholinergic neurons at P1, P5, and P26-P28. This dataset includes multiple brainstem cell types, including OCNs and several other populations of cranial motor neurons. Cholinergic nuclei were labeled using ChAT-Cre to drive expression of the nuclear localized Rosa26-Sun1-GFP reporter. GFP+ cells from the ventral brainstem were selected via fluorescence-activated cell sorting (FACS) and nuclei were captured using the 10x genomics single-cell 3' platform.
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2023-03-11
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