WP5027 - nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
The pathway depicted how nsp1 from SARS-CoV 2 may inhibit translation in the host cell (Yuan S et al 2020, PubMed 33188728). nsp1 protein competes with the EIF3J subunit of the EIF3s complex for binding to the 40S ribosomal subunit. The resulted 43S pre-initiation complex can no longer load the mRNA from the host cell for starting translation.
创建时间：
2025-04-17
