Phytochemical profile and anti-inflammatory effect of Artemisia annua L. essential oil

1.The cell viability of cells treated with different concentrations of AO did not affect cell viability. These data suggested that the AO was non-toxic to RAW264.7. 2.The pre-treated with AO could alleviate the contents of NO, TNF-α, IL-6 produced by LPS. 3. AO showed significant inhibition on the ear edema. 4. AO could inhibited the rise of number of inflammatory cell induced by xylene and the epidermal thickness. 5. The level of TNF-α in the mice pretreated with AO significantly decreased compared to the model group1. 经不同浓度AO处理的细胞，其细胞活力未受影响，上述数据表明AO对RAW264.7细胞无毒性。2. 经AO预处理的细胞可减轻脂多糖（LPS）诱导产生的一氧化氮（NO）、肿瘤坏死因子-α（TNF-α）以及白细胞介素-6（IL-6）的含量。3. AO对耳水肿（ear edema）具有显著抑制作用。4. AO可抑制二甲苯（xylene）诱导的炎症细胞数目升高以及表皮厚度增加。5. 与模型组相比，经AO预处理的小鼠体内肿瘤坏死因子-α（TNF-α）水平显著降低。