Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants
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Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants Descriptor: N-[4-({4-[5-(3,3-DIMETHYLPIPERIDIN-1-YL)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... Authors: Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. Deposit date: 2004-09-17 Release date: 2005-09-17 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
蛋白激酶B选择性抑制剂与蛋白激酶A及其突变体复合物的晶体结构
描述符:N-[4-({4-[5-(3,3-二甲基哌啶-1-基)-2-羟基苯甲酰基]苯甲酰基}氨基)氮杂环庚烷-3-基]异烟酰胺,环腺苷酸依赖型蛋白激酶抑制剂,α型,……
作者:Breitenlechner, C.B、Friebe, W.-G、Brunet, E、Werner, G、Graul, K、Thomas, U、Kuenkele, K.-P、Schaefer, W、Gassel, M、Bossemeyer, D、Huber, R、Engh, R.A、Masjost, B
存储日期:2004年9月17日
发布日期:2005年9月17日
最后修改日期:2024年10月30日
解析方法:X射线衍射(分辨率2.47 Å)
引用文献:Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants, J.Med.Chem., 48, 2005
创建时间:
2004-09-17



