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Supplementary Table S4 from DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

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Figshare2016-05-01 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Supplementary_Table_S4_from_DNMT3A_Haploinsufficiency_Transforms_i_FLT3_i_sup_ITD_sup_Myeloproliferative_Disease_into_a_Rapid_Spontaneous_and_Fully_Penetrant_Acute_Myeloid_Leukemia/22531106
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RNA-Seq gene expression analyses of Flt3ITD/ITD;Dnmt3afl/fl MxCre AML versus Flt3ITD/ITD;Dnmt3afl/fl MPN and comparison of differentially expressed genes to human FLT3-ITD/DNMT3A-mut gene expression and murine AML DMR by GSEA. Lists of AML-unique and HSPC-like genes in human and mouse based on deregulated gene expression found only in the Dnmt3a mutant AML groups or deregulated gene expression in Dnmt3a mutant AML with similar deregulation patterns to normal HSC.
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2016-05-01
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