Non-Hemolytic AMPs Commonly Identified from Cephalopods PSG by Three Prediction Models

The dataset presented here comprises non-hemolytic antimicrobial peptides (AMPs) subsets, which were derived using a consensus prediction approach involving three distinct prediction models. These models were applied to AMPs libraries (DOI: 10.17632/wwk7zzcfhv.1) resulting from the screening of 13 peptide libraries (DOI: 10.17632/6fjsdnvygb.1). These libraries were derived from omics data originating from Cephalopods' Posterior Salivary Glands (DOI: 10.17632/gxmkytwdhx.1).
The provided dataset includes 13 peptide FASTA files, each annotated with information about the enzyme(s) involved in the in silico digestion process. The peptides are categorized based on whether a single enzyme (OE) or two enzymes (TE) were applied, with the latter being applied either sequentially (S) or concurrently (C). These identified non-hemolytic AMPs offer a unique and unexplored chemical landscape, holding great potential for driving the discovery of novel peptide-based pharmaceutical agents.