TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury

ChEBI2013-07-01 更新2026-07-21 收录

肾小管损伤

基质金属蛋白酶抑制剂功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42303 数据链接链接失效反馈

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TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury

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2013-07-01

Expression data from human with IgA nephropathy (IgAN) [HG-U133A]

IgA肾病基因表达

肾小管损伤

Proteinuria is the most important predictor of outcome in glomerulonephritis and experimental data suggest that the tubular cell response to proteinuria is an important determinant of progressive fibr

NIAID Data Ecosystem50

Clinical characteristics and levels of inflammatory and tubular damage markers according to tertile of serum TNFR2 levels in IgAN patients.

IgA肾病生物标记物

肾小管损伤

Data are mean ± SD, median (quartiles), or %. Abbreviations used in this table are the same as in Table 1. NAG, N-acetyl-β-D-glucosaminidase; β2m, β2-microglobulin; L-FABP, liver-type fatty acid bindi

Figshare2015-12-03 更新30

NF-ΚB–MEDIATED INFLAMMATION AS A MECHANISM OF TUBULAR INJURY IN HYPERURICEMIA

肾小管损伤

NF-κB信号通路

Hyperuricemia is increasingly recognized as a significant risk factor for renal tubular injury. Recent studies highlight that elevated uric acid levels can activate NF-κB signaling, triggering pro-inf

Zenodo2026-02-26 更新20

TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury. Mus musculus

肾小管损伤

金属蛋白酶功能

Tissue inhibitors of metalloproteinases (TIMP) are endogenous inhibitors of matrix metalloproteinases (MMP). While TIMP2 and TIMP3 inhibit MMPs, TIMP3 also inhibits activation of pro-MMP2 whereas TIMP

NIAID Data Ecosystem40

miRNA profiles of tubular cells (Rodent A and Rodent B). Rattus norvegicus

疾病miRNA标志物

肾小管损伤

MicroRNAs (miRNAs) are endogenous small RNAs of 18–23 nucleotides that regulate gene expression. Recently, plasma miRNAs have been investigated as biomarkers for various diseases. In the present study

NIAID Data Ecosystem30

TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury

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