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ChIP seq of CDK6-WT and CDK6-K43M in murine BCR-ABL(p185)+ pre/pro B-cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE264219
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资源简介:
The aim of this experiment was to study the DNA interaction of a kinase-dead mutant of the cell cycle kinase CDK6 (CDK6-K43M) in a murine model of BCR-ABL driven leukemia. ChIP seq was performed in mouse BCR-ABL(p185)+ Cdk6-/- pre/pro B cell lines transduced with either HA-tagged wildtype (CDK6-WT), or HA-tagged mutant (CDK6-K43M) CDK6. An antibody against HA was used to pull down the CDK6 variants and associated chromatin.Two replicates per genotype were analysed.
创建时间:
2025-02-26
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